As is well known, Ketamate,this product has been listed as a regulated product globally, and it is very dangerous for anyone to provide or purchase it. It is impossible for legitimate trading companies to provide it.So what should we choose to replace Ketamate?
There are many answers, because there are many derivatives that are similar to Ketamate in chemical molecular structure and have similar effects. Among the numerous derivatives, there are two products that stand out, namely 2FDCK and DCK. So what are the differences between these two? We should learn more to help us make the initial choice.
2FDCK vs DCK,what is the similarities?
What are the differences and similarities between 2FDCK and DCK in terms of effectiveness, dosage, and structure
As similar compounds to Ketamine, they are all developed based on the structure of K. The seats are relatively similar in terms of chemical structure, mechanism of action, and effectiveness.
Similarities:
1. The chemical structure is similar, all of which are cyclohexylamine derivatives, except that 2FDCK introduces a fluorine atom to replace a chlorine atom on the cyclohexane ring.
2. The mechanism of action is the same, both of which are NMDA receptor antagonists, which produce absentmindedness and dissociation effects by blocking the action of glutamate.
3. The types of effects are similar, and they can all produce effects such as weightlessness, external experiences, and fantasy experiences, which significantly affect spatiotemporal perception and self-awareness.
Since they are two different products and can stand out among numerous derivatives, they must all have their own advantages.
when 2FDCK vs DCK,the different is as below:
1. In terms of efficacy, 2FDCK and 2F have stronger hallucinogenic effects, and their effects are more pronounced and long-lasting at the same dose. This is because fluorine atoms enhance their liposolubility and ability to penetrate the blood-brain barrier.
2. From the side effects of the product, 2FDCK has smaller side effects, especially with lighter obstacles to body coordination and motor ability. This may be related to the weak antagonism effect on 5-HT2A receptor.
From the perspective of half-life, 2FDCK takes effect faster and disappears faster. Fluorine atoms accelerate its absorption and metabolism, leading to rapid onset and short action time. And the half-life of DCK is relatively long.
4. In terms of dosage, the dosage of 2FDCK is usually lower, usually between 10-30mg. The commonly used dose range for DCK is between 30-100mg.
5. Due to the shorter structure and half-life of 2FDCK, it is relatively difficult to detect. Previously, conventional drug testing was difficult to detect its presence, making it a preferred choice for some users. However, with the popularity of 2FDCK, many countries have become increasingly strict in its testing, and some countries have already included 2FDCK in the list of controlled substances.
We are not sure about the future direction, but the only certainty is that due to the huge demand in the market, there will be more new material products to replace 2FDCK, just like 2FDCK replacing Ketamate.
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